The Spain international was caught by Enzo Perez at the Mestalla and was replaced by Ivan Rakitic as the injuries continue to mount up for Luis Enrique.
Andres Iniesta was left in tears after being stretchered off in the early stages of Barcelona’s clash with Valencia.
The Spain international was caught by Enzo Perez at the Mestalla, and a stretcher was called for immediately as he was replaced by Ivan Rakitic.
The 2010 World Cup winner looked to have injured his knee as he stretched for the ball, suggesting he may have suffered ligament damage.
A serious injury could see the midfielder miss upcoming matches against Manchester City and Real Madrid as the injury problems mount up for Luis Enrique.
Jordi Alba and Gerard Pique both picked up injuries against City on Wednesday, and will miss the return fixture at the Etihad Stadium.